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  |  | Current Results of Our ResearchThese pages, marked with 
GREEN headings, are published for 
comment and criticism. These 
are not our final findings; some of these opinions will probably change.   
LOG OF UPDATES   CRN Research: Overview of Current Findings    
 
   Thirty Essential Nanotechnology Studies - #6Overview of all studies: Because of the largely 
unexpected transformational power of molecular manufacturing, it is urgent to 
understand the issues raised. To date, there has not been anything approaching 
an adequate study of these issues. CRN's recommended series of
thirty essential studies 
is organized into five sections, covering fundamental theory, possible 
technological capabilities, bootstrapping potential, product capabilities, and 
policy questions. Several preliminary conclusions are stated, and because our 
understanding points to a crisis, a parallel process of conducting the studies 
is urged.   CRN is actively looking for researchers interested in 
performing or assisting with this work. Please contact CRN Research Director
Chris Phoenix if you would like more information or if you have comments on 
the proposed studies.  
  
    | Study #6 | What 
    other chemistries and options should be studied? |  
    |  | This is a grab bag 
    of questions intended to suggest possibilities that may have been 
    overlooked. |  
    | Subquestion | What other 
    chemistries may be suitable for atomically precise programmable assembly? |  
    | Preliminary answer | Merkle has 
    suggested small cubical molecules with boron and nitrogen. Phoenix and 
    Toth-Fejel
    
    suggested POSS (polyhedral oligomeric silsesquioxane) as an early 
    building block. Silica is interesting, especially since its deposition can 
    be catalyzed by proteins such as R5. Perhaps precise metal nanoparticles 
    could be fused. Other possibilities no doubt will be offered. |  
    | Subquestion | What is the 
    potential of top-down technologies using imprecise chemistry, in terms of 
    self-manufacture and device performance? (e.g. extrusion, DPN, metal-over-buckytube, 
    MEMS, inkjet, stereolithography, masked or hologram-switched optical surface 
    activation) |  
    | Preliminary answer | Some of these 
    appear to have fairly high throughput. Many are flexible in the materials 
    they can deposit. More work will be needed to determine what kinds of 
    devices, especially bearing surfaces, can be made with these imprecise 
    technologies. |  
    | Subquestion | What about 
    atom holograms and atom lasers? |  
    | Preliminary answer | Unknown. Atom 
    holograms, a way of programmably redirecting a beam of atoms into complex 
    deposition patterns, were
    
    demonstrated in Japan several years ago, and have not made a lot of news 
    since. Atom laser is a confusingly similar name for a very different 
    technology: a way to reduce a cloud of atoms to a single quantum state, 
    making them extremely controllable. The technologies may be synergistic. |  
    | Subquestion | Are there 
    synergies between any of the considered technologies, making problems easier 
    to solve or improving performance of a technology? |  
    | Preliminary answer | Almost certainly. |  
    | Conclusion | Molecular manufacturing may be easier than we realize. Many possibly 
    helpful technologies have not yet been assessed. There's no way to know 
    without studying multiple alternatives. 
 |  
    | Other studies | 1. 
    Is 
    mechanically guided chemistry a viable basis for a manufacturing technology? 2. To what extent is molecular manufacturing counterintuitive and 
    underappreciated in a way that causes underestimation of its importance?
 3. What is 
    the performance and potential of diamondoid machine-phase chemical 
    manufacturing and products?
 4. What is the performance and potential of biological programmable 
    manufacturing and products?
 5. What is the performance and potential of nucleic acid 
    manufacturing and products?
 
 7. What 
    applicable sensing, manipulation, and fabrication tools exist?
 8. What will be required to develop diamondoid machine-phase chemical 
    manufacturing and products?
 9. What will be required to develop biological programmable 
    manufacturing and products?
 10. What will be required to develop nucleic acid manufacturing and 
    products?
 11. How rapidly will the cost of development decrease?
 12. How could an effective development program be structured?
 13. What is 
    the probable capability of the manufacturing system?
 14. How capable will the products be?
 15. What will the products cost?
 16. How rapidly could products be designed?
 17. Which 
    of today's products will the system make more accessible or cheaper?
 18. What new products will the system make accessible?
 19. What impact will the system have on production and distribution?
 20. What effect will molecular manufacturing have on military and 
    government capability and planning, considering the implications of arms 
    races and unbalanced development?
 21. What effect will this have on macro- and microeconomics?
 22. How can proliferation and use of nanofactories and their products 
    be limited?
 23. What effect will this have on policing?
 24. What beneficial or desirable effects could this have?
 25. What effect could this have on civil rights and liberties?
 26. What are the disaster/disruption scenarios?
 27. What effect could this have on geopolitics?
 28. What policies toward development of molecular manufacturing does 
    all this suggest?
 29. What policies toward administration of 
    molecular manufacturing does all this suggest?
 30. How can appropriate policy be made and implemented?
 
 |  
    | Studies should begin 
    immediately. | The situation is 
    extremely urgent. The stakes are unprecedented, and the world is unprepared. 
    The basic findings of these studies should be verified as rapidly as 
    possible (months, not years). Policy preparation and planning for 
    implementation, likely including a crash development program, should begin 
    immediately. |  DEVIL'S ADVOCATE — 
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